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Advantages of Dry Granulation

February 12, 2024

As one of the most common granulation methods, dry granulation has several advantages. This is what makes it preferred to wet granulation. Some of these benefits include;

Cost-effective Granulation Method

The cost of manufacturing granules through dry granulation is usually quite low. This means that the process is cost-effective. Another aspect that shows the cost-effectiveness of dry granulation is the high production volume of both roller compactors and slugging machines.

Flexible for Small and Large-scale Production

Most large-scale manufacturing systems are unable to cope with low-volume production for various reasons. For dry granulation, it is completely different. Whether you are planning to manufacture dry granules for personal or commercial use, dry granulation is perfectly suited to handle this process.

The Equipment Takes up a Small Space

Dry granulation machines, for example, the Roller Compactor, are sizeable compared to what it is capable of manufacturing. One of the reasons for this observation is that the end product and the feedstock are usually small in size.

Involves Fewer Unit Processes

Essentially, there are at most four steps in the dry granulation technique. We discussed these steps in a previous section where we talked about the dry granulation process.

The advantage of this technique having few processes reflect on the production volume of the dry granules. In other words, the manufacturer can produce large quantities of granules. In business, an increase in production volume automatically means more revenue for the business.

Produces Stable Products

The stability of products is quite essential, especially in the pharmaceutical industry. In this case, stability means the ability of the granules to retain shape and size. While some of the dry granules crumble easily, most of them manage to retain their shape under stressful conditions.

Excellent for Moisture-sensitive Drugs

Dry granulation is an excellent manufacturing technique for drugs that are sensitive to moisture. This includes drugs that have active elements that react poorly when they come into contact with moisture content.

Dry Granulator

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Author:

Mr. Keven Lee

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