What is dry granulation

There are many definitions of dry granulation process. However, all of them revolve around one singular idea - producing granules from dry powder without adding any water. Dry granulation relies on compaction and compression techniques to pack the dry powder in a way that it will not crumble easily. This is quite challenging, but the machines used for dry granulation are effective.

The reason why this method exists is to aid in the manufacturing of granules that are sensitive to moisture or any solvents in the forming process.

Dry granulation techniques are carried out using specific machines that can produce the necessary pressure and compression to form the granules. Also, these machines are required to dispense the right amount of powder for granule formation.

One of the major challenges of dry granulation is that sometimes the dry powder may not flow at a constant rate, thereby affecting the granulation. Specifically, the lack of a uniform flow rate could potentially lead to granules with varying weights and shapes. These challenges will become clearer as you learn more about how this process occurs.