Western medicine dry granulator roller compaction

Western medicine dry granulator roller compaction

$28000-120000 /Set/Sets

Payment Type:	T/T,L/C
Incoterm:	FOB,CFR,CIF,EXW,FCA
Min. Order:	1 Set/Sets
Transportation:	Ocean,Land,Air
Port:	Shanghai,Ningbo,Guangzhou

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Product Description

Product Attributes

Model No.: LG

Brand: Lead machinery

Place Of Origin: China

Old And New: New

Machine Type: Granulator

Video Factory Inspection: Provided

Mechanical Test Report: Provided

Core Component Warranty Period: 1 Year

Core Components: Plc, Gearbox, Motor

Warranty Period: 1 Year

Core Selling Point: Famous Brand Plc

Applicable Industry: Food &Amp; Beverage Factory, Energy &Amp; Mining, Other

Out-of-warranty Service: Field Maintenance And Repair Service, Video Technical Support, Online Support, Spare Parts

Where To Provide Local Services (in Which Countries Are There Overseas Service Outlets): Italy, Russia, Spain, Thailand, Japan, Indonesia

Showroom Location (in Which Countries Are There Sample Rooms Overseas): Italy, Malaysia, Australia, Pakistan, Viet Nam, Turkey, Canada, Thailand

Function: Dry granulation

Material Of Machine: SUS304/SUS316L

Material Of Roller: 3Cr13

Control System: Touch screen & PLC

Pressure Range: 0~25Mpa

Hydraulic Station: 0.75kW

Standard: GMP

Brand Of Control System: Siemens

Explosion-proof: Option

Customized: Support

Packaging & Delivery

Selling Units	:	Set/Sets
Package Type	:	Wooden case
Picture Example	:

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ROLLER COMPACTOR

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Product Description

Roller compacor is one of the most important Granulation Equipment in pharmaceutical industry. Dry granulation is used for increasing the bulk density of powders, while increasing the particle size, resulting in better flowing material, which is a prerequisite for manufacturing capsules and tablets on high speed production equipment.

Furthermore, bonding the particles of various substances together during the compaction process reduces the tendency to segregation of powder particles of different substances. This results in an improvement of the homogeneity of the active ingredients (API) within the powder blend, causing an improvement of dose uniformity of such dosage forms.

The granules samples that made by roll compaction dry granulator

Roller compactors can be divided into two categories: One is equipped with a fixed gap, the other one with a floating gap. Both consist of the three major units as explained above but differ in the way in which the smallest distance (gap) between the rolls is realized.

When a fixed gap is installed, the amount of powder drawn in into the compaction area between the rolls is inconsistent, which results in varying forces applied to the powder bed. Like slugging, this will cause large fluctuations in the ribbon and granulate properties.

The roll compactor of Lead Machinery is floating gap type.

Technical advantages of LG series Roller compactor:

Roller Compactors with variable gap

With floating gap the distance between the rolls change according to the amount of powder provided. The force applied to the powder remains constant. This ensures that property fluctuations in the granules are reduced to a minimum.

Milling

With our integrated models, the ribbons are milled immediately after compaction using a screen with a given mesh size, thus limiting the upper particle size.

This milling process should be performed as gently as possible, so as to avoid creating excess fines.

Process Analytical Technology (PAT)

The LG series roller compactors are able to control and measure all product quality relevant parameters (e.g. force, gap and roll speed) on-line in order to fulfill the requirements of the pharmaceutical industry for a well-controlled and documented manufacturing process. All the parameters are calibrated and validated. Additionally, in order to cope with batch to batch variations, our machines are fitted with control systems to allow equal granule properties during manufacturing according to PAT.